PhosphoExploration

TM

21st Century Biochemicals introduces PhosphoExploration TM , an integrated approach for the identification, localization, and study of novel protein phosphorylation sites. The PhosphoExploration TM Program allows researchers to obtain phosphopeptides and/or phosphospecific antibodies to either previously characterized phosphorylation sites, or to have the MS and Analytical Services Laboratory at 21st Century Biochemicals, headed by Dr. Eric Berg, localize novel sites of phosphorylation prior to the generation of specific phosphopeptides and phosphospecific antibodies. With a state of the art Mass Spectrometry laboratory featuring LC-MS/MS, including the QSTAR XL Q-oTOF quadrapole hybrid and MALDI-TOF, and with 2D gel electrophoresis, nano and capillary LC capabilities, our staff isolates and sequences phosphopeptides from phosphorylated proteins, identifying the specific site(s) of phosphorylation. Working hand in hand with our peptide chemists and immunology staff, we can then generate phosphopeptides, including cell permeable peptides for cellular studies, as well as produce high quality phosphorylation state-specific antibodies, providing a start to finish, integrated solution. The introduction of our PhosphoExploration TM Program reinforces our goal to provide "Integrated Solutions for Complex Proteomic Problems." For more information, please contact the Company.