labeled/unlabeled peptide pairs, many other options available!
CitationsOur scientists work with some of the most distinguished laboratories and proteomic centers across the globe. Our CSO was also part of the CPTAC (Clinical Proteomic Tumor Analysis Consortium) Working Group that recently published recommendations for the production of optimal peptides for MS-based (e.g., SRM/MRM) assays:Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry–Based Assays. Andrew N. Hoofnagle, Jeffrey R. Whiteaker, Steven A. Carr, et al. Clin. Chem., Jan 2016; 62: 48 - 69.CPTAC packages are also available which include epitope design, antibody production, along with isotopically-labeled peptides for use in biomarker discovery platforms. We are also proud to the supplier to some of the world’s foremost scientists and scientific institutions, including the: Broad Institute of MIT/Harvard, Harvard Medical School, Pfizer, NIH, KIST (Korean Institute for Science and Technology), Fred Hutchinson Cancer Center, FDA, University of Washington, UT-Southwestern Medical Center, Dana Farber Cancer Institute, and many, many others (see examples of publications below).The Broad Institute of MIT and Harvard:Simplified and Efficient Quantification of Low-abundance Proteins at Very High Multiplex via Targeted Mass Spectrometry. Michael W. Burgess, Hasmik Keshishian, D. R. Mani, Michael A. Gillette, and Steven A. Carr. Mol. Cell. Proteomics, Apr 2014; 13: 1137 - 1149.The Korean Institute for Science and Technology and Seoul National University:Both Targeted Mass Spectrometry and Flow Sorting Analysis Methods Detected the Decreased Serum Apolipoprotein E Level in Alzheimer's Disease Patients. Sun-Ho Han, Jun Seok Kim, Youngju Lee, Heesun Choi, Jong-Won Kim, Duk Lyul Na, Eun Gyeong Yang, Myeong-Hee Yu, Daehee Hwang, Cheolju Lee, and Inhee Mook-Jung. Mol. Cell. Proteomics, Feb 2014; 13: 407 - 419.The FDA, College Park, MD:Quantification of Allergenic Bovine Milk αS1-Casein in Baked Goods. Using an Intact 15N-Labeled Protein Internal Standard. G. Asher Newsome and Peter F. Scholl* J. Agric. Food Chem. 2013, 61, 5659−5668.Fred Hutchinson Cancer Center/University of Washington: Sequential Multiplexed Analyte Quantification Using Peptide Immunoaffinity Enrichment Coupled to Mass Spectrometry. Jeffrey R. Whiteaker, Lei Zhao, Chenwei Lin, Ping Yan, Pei Wang, and Amanda G. Paulovich. Mol. Cell. Proteomics, Jun 2012; 11: M111.015347.Pfizer: Identification and quantification of osteopontin splice variants in the plasma of lung cancer patients using immunoaffinity capture and targeted mass spectrometry. Jiang Wu, Pooja Pungaliya, Eugenia Kraynov, and Brian Bates. Biomarkers, 2011, 1–9, 20 November 2011The Broad Institute of MIT and Harvard and the Fred Hutchinson Cancer Center: Evaluation of Large Scale Quantitative Proteomic Assay Development Using Peptide Affinity-based Mass Spectrometry. Jeffrey R. Whiteaker, Lei Zhao, Susan E. Abbatiello, Michael Burgess, Eric Kuhn, Chen Wei Lin, Matthew E. Pope, Morteza Razavi, N. Leigh Anderson, Terry W. Pearson, Steven A. Carr, and Amanda G. Paulovich. Mol. Cell. Proteomics, Apr 2011; 10: M110.00564.