Is There an Advantage to Using a Synthetic Peptide to Manufacture My
Antibody?
Antibodies can be made from expressed or native protein, proteins separated by gel electrophoresis
and the appropriate band excised, chromatographically purified tryptic peptides, heat or
formaldehyde-inactivated viruses, and synthetic peptides. The use of synthetic peptides, owing in
part to their minimal cost and purity, can be used to produce antibodies in a variety of species (e.g.,
rabbit, goat, sheep, mouse, rat, chickens). In addition, during the synthetic process, post-
translational modifications (PTMs) can be added at specific site(s) along the peptide chain, allowing
for the production of antibodies selective not only for the peptide's primary sequence, but for one or
more PTMs as well. The most common PTM studied with the use of specific antibodies is
phosphorylation. The scientists at 21st Century Biochemicals have many years of experience
producing antibodies selective for the phosphorylation state of the peptide as well as the parent
protein.
100% MADE IN THE USA Since 2003 ISO 9001:2015 Certified Peptide Manufacturer